FIGURE 1.
Nonobese diabetic (NOD) severe combined immunodeficiency (SCID) γc−/− mice mount an innate immune response to human skin grafts. Human skin grafts harvested and stained with hematoxylin-eosin or for the presence of mouse neutrophils (Ly-6c, Gr-1) (n=4 per group). (A and B) hematoxylin-eosin of C.B.-17 SCID/bg mouse and NOD SCID γc−/−, respectively; (C and D) IHC for mouse neutrophils of C.B-17 SCID/bg mouse and NOD SCID γc−/−, respectively. 400× magnification of mouse neutrophils (D-inset).
