Figure 8.
Viral load and clinical disease enhancement occurred in vaccinates. a. Mean log plasma viral loads on each day tested for controls (thin red line) and vaccinates (thin blue line). Error bars are standard error. The bold lines are 2nd order smoothed curves for controls (red) and vaccinates (blue). b. Geometric mean plasma viral loads on each day tested for controls and vaccinates. Horizontal lines are medians. c. Initial peak plasma viral load for controls and vaccinates. Horizontal lines are geometric means. d. Initial peak plasma viral loads for ponies that had vaccine-elicited CTL compared with those that did not. Horizontal lines are geometric means. e. Percent days plasma viral load exceeded 10,000 RNA copies/ml for controls and vaccinates. Horizontal lines are means. f. Percent days plasma viral load exceeded 10,000 RNA copies/ml for ponies that had vaccine-elicited CTL compared with those that did not. Horizontal lines are means. g. Percent days platelet counts were at least 3 SD below the pre-challenge mean for controls and vaccinates. Horizontal lines are means. h. Percent days platelet counts were at least 3 SD below the pre-challenge mean for ponies that had vaccine-elicited CTL compared with those that did not. Horizontal lines are means.