FIG. 5.
Agilent oligonucleotide microarray. (A) Noncontact inkjet printing technology delivers a small and accurate volume (picoliters) of nucleotides to the first layer on the microarray surface. (B) Repeated rounds of base-by-base printing extend the length of specific oligonucleotide probes. (C) Close-up of growing oligonucleotide chain with a base being added. (D) The final product is a 60-mer in situ-synthesized probe as a feature on a microarray containing thousands of specifically synthesized probes. (Images courtesy of Agilent Technologies.)