Abstract
Tankersley, Robert W., Jr. (Medical College of Virginia, Richmond). Amino acid requirements of herpes simplex virus in human cells. J. Bacteriol. 87:609–613. 1964.—Progressive infection of human cells minimally infected with herpes simplex virus requires 11 of the amino acids of Eagle's medium, and glutamine. Lysine is not required, but rather exerts a partially inhibitory effect upon virus multiplication. Infected cells deprived of arginine support neither cytopathogenic effects nor virus replication; when arginine is replaced, a prompt and extensive infection follows. The effect of nutritional deficiencies on virus infection is discussed.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BADER J. P., MORGAN H. R. Latent viral infection of cells in tissue culture. VI. Role of amino acids, glutamine, and glucose in psittacosis virus propagation in L cells. J Exp Med. 1958 Nov 1;108(5):617–630. doi: 10.1084/jem.108.5.617. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BADER J. P., MORGAN H. R. Latent viral infection of cells in tissue culture. VII. Role of water-soluble vitamins in psittacosis virus propagation in L cells. J Exp Med. 1961 Feb 1;113:271–281. doi: 10.1084/jem.113.2.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- EAGLE H., HABEL K. The nutritional requirements for the propagation of poliomyelitis virus by the HeLa cell. J Exp Med. 1956 Aug 1;104(2):271–287. doi: 10.1084/jem.104.2.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- EAGLE H. Nutrition needs of mammalian cells in tissue culture. Science. 1955 Sep 16;122(3168):501–514. doi: 10.1126/science.122.3168.501. [DOI] [PubMed] [Google Scholar]
- FARNHAM A. E. The formation of microscopic plaques by herpes simplex virus in HeLa cells. Virology. 1958 Oct;6(2):317–327. doi: 10.1016/0042-6822(58)90085-0. [DOI] [PubMed] [Google Scholar]
- KENNY G. E., POLLOCK M. E. Mammalian cell cultures contaminated with pleuropneumonia-like organisms. I. Effect of pleuropneumonia-like organisms on growth of established cell strains. J Infect Dis. 1963 Jan-Feb;112:7–16. doi: 10.1093/infdis/112.1.7. [DOI] [PubMed] [Google Scholar]
- LEWIS V. J., Jr, SCOTT L. V. Nutritional requirements for the production of herpes simplex virus. I. Influence of glucose and glutamine of herpes simplex virus production by HeLa cells. J Bacteriol. 1962 Mar;83:475–482. doi: 10.1128/jb.83.3.475-482.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MELNICK J. L., HSIUNG G. D., RAPPAPORT C., HOWES D., REISSIG M. Factors influencing the proliferation of viruses. Tex Rep Biol Med. 1957;15(3):496–533. [PubMed] [Google Scholar]
- MORGAN H. R., BADER J. P. Latent viral infection of cells in tissue culture. IV. Latent infection of L cells with psittacosis virus. J Exp Med. 1957 Jul 1;106(1):39–44. doi: 10.1084/jem.106.1.39. [DOI] [PMC free article] [PubMed] [Google Scholar]
- PEARSON H. E., LAGERBORG D. L., WINZLER R. J. Effects of certain amino acids and related compounds on propagation of mouse encephalomyelitis virus. Proc Soc Exp Biol Med. 1952 Mar;79(3):409–411. doi: 10.3181/00379727-79-19395. [DOI] [PubMed] [Google Scholar]
- PLEDGER R. A., POLATNICK J. Defined medium for growth of foot-and-mouth disease virus. J Bacteriol. 1962 Mar;83:579–583. doi: 10.1128/jb.83.3.579-583.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SYVERTON J. T., McLAREN L. C. Human cells in continuous culture. I. Derivation of cell strains from esophagus, palate, liver, and lung. Cancer Res. 1957 Oct;17(9):923–926. [PubMed] [Google Scholar]
- THOMAS W. J., ZIEGLER D. W., SCHEPARTZ S. A., McLIMANS W. F. Use of arginine to eliminate medium changes in tissue culture systems. Science. 1958 Mar 14;127(3298):591–592. doi: 10.1126/science.127.3298.591. [DOI] [PubMed] [Google Scholar]
