Fig. 7.
Syncytia formation mediated by F mutants L486A and I488A containing a second destabilizing mutation. Representative micrographs of syncytia formed in BHK-21F cells 20 h p.t. Cells were cotransfected with pCAGGS HN DNA and pCAGGS DNA encoding wt F, F L486A, or F I488A, the hyperfusogenic mutants F S443P, F G105A, or F G109A, or the double mutants containing a hyperfusogenic mutation and also F L486A or F I488A.
