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. 2003 Jun 10;88(12):1979–1986. doi: 10.1038/sj.bjc.6601005

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Copyright © 2003 Cancer Research UK

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After anti-VEGF mAb therapy, large-vessel VD decreases (P=0.03) while intratumoral H33342, injected 1 min before killing as indicator of tumour perfusion, increases (P=0.01). There is a trend to higher intratumoral concentration of CPT-11 in the anti-VEGF-mAb-treated group (P=0.09). Asterisks, P<0.05 vs placebo. Data indicate mean±s.e.