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Aortic root intimal plaque lipid and collagen content. Aortic root sections from TGF-β1-overexpressing mice (DT-off) and littermate controls (ST-off), all fed a high-fat diet for 12 wks, were analyzed for: plaque lipid content, determined by oil red O stain (A) and plaque collagen content, measured by picrosirius red birefringence (B). Data points represent individual aortae; bars are group medians.
