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. Author manuscript; available in PMC: 2009 Sep 3.
Published in final edited form as: Mol Ther. 2008 Apr 1;16(6):1056–1064. doi: 10.1038/mt.2008.60

Figure 2. AAV-IGF-1-promoted motor neuron survival and delayed death in amyotrophic lateral sclerosis mice.

Figure 2

Motor neuron counts in (a) cervical, (b) thoracic, (c) lumbar, and (d) sacral regions of the spinal cord. Kaplan–Meier survival analysis of AAV1-IGF-1-, AAV2-IGF-1-, AAV1-GFP-, and AAV2-GFP-treated animals (e). Mice were scored as dead when they could no longer right themselves within 30 seconds of being placed on their back. Green fluorescent protein (GFP)-treated mice are indicated in green and insulin-like growth factor-1 (IGF-1)-treated mice are indicated in red. AAV, adeno-associated virus; WT, wild type.