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. 2009 Aug 24;186(4):525–540. doi: 10.1083/jcb.200905070

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© 2009 Rolland et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 7. — CED-9(R211E, N212G) is less effective in the promotion of mitochondrial fusion. (A) Schematic of the mitochondrial morphologies observed in embryos. (B) Transgenic lines overexpressing mitogfp in combination with ced-9(N158A, A159G, Q160A) (P_HSmitogfp + P_HSced-9(N158A, A159G, Q160A)) or ced-9(R211E, N212G) (P_HSmitogfp + P_HSced-9(R211E, N212G)) were analyzed by Nomarski optics and fluorescent microscopy. The outline of cells is indicated in the schematic of the mitochondrial network. Quantification of the different mitochondrial morphologies observed and the number of embryos and transgenic lines analyzed are indicated.