Table 5.
Up-regulation compared with looking at pictures within the spider and the aversive category and for spider—aversive pictures for the early, middle and late phase
| Early |
Middle |
Late |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Contrast | Region | Side | x y z | t | x y z | t | x y z | t | |
| Up–Look | |||||||||
| Spider | ROI analyses | ||||||||
| vmPFC | L | −12 36 −12 | 3.54 | – | – | ||||
| dACC | L | −3 18 30 | 4.64 | −3 15 33 | 4.83 | – | |||
| R | 6 12 39 | 4.36 | 6 12 33 | 4.64 | – | ||||
| rACC | L | 0 36 0 | 4.05 | – | – | ||||
| R | 3 36 −3 | 3.84 | – | – | |||||
| vlPFC | L | −42 9 18 | 4.63 | −48 6 6 | 5.00 | – | |||
| R | 48 12 0 | 3.88 | – | – | |||||
| R | 63 12 21 | 3.78 | – | – | |||||
| Amygdala | L | −27 −3 −18 | 3.27 | – | – | ||||
| R | 24 0 −15 | 3.89 | – | – | |||||
| Insula | L | −45 6 6 | 3.86 | −45 6 6 | 4.56 | – | |||
| R | 39 9 −9 | 4.60 | 36 9 3 | 3.79 | – | ||||
| R | – | 27 18 −21 | 3.79 | – | |||||
| Exploratory analysis | |||||||||
| Precentral gyrus | R | 24 −21 69 | 6.71 | – | – | ||||
| Supramarginal gyrus | L | −57 −36 24 | 5.15 | – | – | ||||
| Aversive | ROI analyses | ||||||||
| dlPFC | L | −12 57 30 | 4.54 | −21 69 9 | 5.13 | – | |||
| L | −33 15 54 | 4.05 | −36 18 51 | 3.93 | – | ||||
| L | −30 66 3 | 3.98 | – | – | |||||
| R | 24 51 36 | 4.28 | – | – | |||||
| dmPFC | L | −9 54 6 | 4.92 | −3 66 3 | 3.96 | – | |||
| R | 9 63 21 | 3.94 | – | – | |||||
| dACC | L | −6 9 39 | 4.03 | −3 18 33 | 3.59 | – | |||
| R | 12 9 36 | 4.57 | 3 15 42 | 3.85 | – | ||||
| rACC | L | −3 36 30 | 4.14 | – | – | ||||
| L | −3 51 3 | 3.86 | – | – | |||||
| vlPFC | L | −48 9 0 | 4.73 | −51 3 6 | 4.68 | – | |||
| R | 63 21 3 | 4.05 | – | – | |||||
| Amygdala | L | −30 3 −18 | 3.60 | – | – | ||||
| R | 30 3 −21 | 3.60 | – | – | |||||
| Insula | L | −45 9 −3 | 3.95 | −48 3 3 | 4.56 | – | |||
| R | – | 39 6 −6 | 3.91 | – | |||||
| Exploratory analysis | |||||||||
| Calcarine fissure | L | – | −6 −99 0 | 6.39 | – | ||||
| Superior temporal pole | R | – | 66 3 3 | 5.45 | – | ||||
| Cerebellum | R | – | 15 −90 −33 | 5.45 | – | ||||
| Spider–Aversive | ROI analyses | ||||||||
| rACC | L | 0 36 −3 | 3.66 | – | – | ||||
| R | 3 36 −3 | 3.48 | – | – | |||||
| Look–Up | |||||||||
| Spider | Exploratory analysis | ||||||||
| Inferior parietal gyrus | R | – | – | 39 −66 57 | 5.97 | ||||
The contrast up–look for aversive–spider pictures showed no significant exploratory results; side: hemisphere; L: left; R: right; x y z: MNI coordinates; t: maximum t-value.