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. 2008 Oct 9;168(10):1099–1109. doi: 10.1093/aje/kwn237

Table 2.

Relation Between Time at Risk (Number of Years Since Onset of Drug Injection) and HCV Prevalence in Injection Drug Users in 72 Studies and 293 Categories of Time at Risk, HCV Synthesis Project, 1989–2006

Parameter Estimate SE 95% CI
Lower Bound Upper Bound
Intercept −0.82 0.17 −1.16 −0.47
Time at risk** 0.18 0.01 0.16 0.20
Centered quadratic time at risk** −0.20 0.02 −0.23 −0.16
Recruitment before 1995** 0.72 0.22 0.28 1.16
Developing/transitional country* 1.10 0.38 0.35 1.84

Abbreviations: CI, confidence interval; HCV, hepatitis C virus; SE, standard error.

* P < 0.05; **P < 0.01; type III tests of fixed effects as estimated by generalized mixed-effects meta-regression.