Table 2.
FDG-PET—comparisons of FTLD and CBS groups
| Hemisphere | Area | x | y | z | Brodmann Area | Cluster size | T-score |
|---|---|---|---|---|---|---|---|
| FTD < NC | |||||||
| R | Dorsolateral prefrontal cortex | 54 | 27 | 30 | 46 | 7869 | 7.42 |
| L&R | Dorsomedial prefrontal cortex | −6 | 48 | 42 | 8/10 | – | 6.85 |
| R | Posterior parietal cortex | 54 | −57 | 48 | 40 | 417 | 4.67 |
| CBS < NC | |||||||
| R | Superior Parietal Lobule | 36 | −57 | 60 | 7 | 4891 | 5.57 |
| R&L | Posterior cingulate gyrus | 9 | −15 | 27 | 23 | 945 | 4.09 |
| R | Thalamus | 0 | −15 | 3 | – | – | 3.67 |
| L | Anterior superior/middle frontal gyrus | −33 | 66 | 0 | 10/9 | 1097 | 4.01 |
| FTD < CBS | |||||||
| L&R | Dorsomedial prefrontal cortex | −9 | 45 | 42 | 8/9 | 5647 | 5.29 |
| L | Anterior inferior temporal cortex | −51 | −9 | −30 | 20 | 21 | 3.09 |
| CBS < FTLD | |||||||
| R&L | Postcentral/superior parietal/precuneus | 30 | −45 | 60 | 5/7 | 10171 | 6.59 |
FDG-PET analysis using SPM5. Only areas exceeding a voxel level threshold of P = 0.005 uncorrected, five voxels and FWE-corrected or cluster-corrected P = 0.05 over the whole brain or the bilateral apriori aTL ROI are reported. Side maxima in larger clusters are marked in italics.