Figure 4.

Naïve CD4+ T cells cultured with IL-33-activated DCs produce IL-5 and IL-13. CD4+ T cells isolated from naïve B6 or naïve OT-II mice were cultured with or without DCs and IL-33 for 6 or 10 days; no antigens were added. Supernatants were analyzed for cytokines on day 6 (IL-4, IL-13, and IFN-γ) and on day 10 (IL-5). *p<0.05, compared to medium alone, n=6.