Fig. 8.
Estradiol-17β bolus increased phosphorylation of CREB in CA1 pyramidal neurons. Confocal images of hippocampal CA1 region depicting co-localization of immunoreactivities for neuronal marker NeuN (red) and pCREB (green) (40× magnification, scale bar=50 µM) at 48 h after 17β-estradiol treatment to OvX rats. Note (E, F) the increase in pCREB immunoreactivity in 17β-estradiol-treated OvX rats as compared to untreated OvX rat. For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.
