FIG. 4.
Effect of FcγR expression on HIV-1 neutralization by plasma samples from infected individuals. The neutralizing activities of plasma samples from individuals who were chronically infected with either HIV-1 subtype C (BB12, BB24, BB34, and BB87) or subtype B (HIV 011, HIV 012, HIV 013, HIV 014, 1648, 1652, and 1686) were assessed against two subtype B viruses (700010040.C94520 and QH0692.42) and two subtype C viruses (CAP45.2.00.G3 and ZM197M.PB7) in parental TZM-bl cells (black bars) and in TZM-bl cells expressing FcγRI (left-hatched bars), FcγRIIa (gray bars), FcγRIIb (right-hatched bars), and FcγRIIIa (horizontally hatched bars). Fifty percent inhibitory dose (ID50) neutralization titers that were below the level of detection (dilution of <1:20) were assigned a value of 10 and are not visible.