Table 3.
Upregulated genes previously found to be overexpressed in pancreatic cancer
| Symbol | Gene name | Accesion number | Fold change | p Value | Reference |
|---|---|---|---|---|---|
| ACTG2 | Actin, gamma 2, smooth muscle, enteric | NM_001615 | 11.23 | 1.26E-19 | 18 |
| ADAM8 | ADAM metallopeptidase domain 8 | NM_001109 | 3.50 | 7.48E-12 | 30 |
| ADM | Adrenomedullin | NM_001124 | 2.59 | 8.28E-08 | 30 |
| AGT | Angiotensinogen | NM_000029 | 19.86 | 7.04E-21 | 28 |
| BIRC3 | Baculoviral IAP repeat-containing 3 | NM_001165 | 2.51 | 2.06E-07 | 19 23 28 |
| BOK | BCL2-related ovarian killer | NM_032515 | 5.33 | 1.82E-15 | 20 |
| CD9 | CD9 antigen | NM_001769 | 2.40 | 1.24E-06 | 18 |
| CLDN1 | Claudin 1 | NM_021101 | 2.50 | 5.09E-05 | 19 |
| COL11A1 | Collagen, type XI, alpha 1 | NM_080629 | 4.03 | 5.81E-13 | 19 21 |
| C1S | Complement component 1, s subcomponent | NM_001734 | 2.85 | 1.26E-09 | 30 |
| CYGB | Cytoglobin | NM_134268 | 2.86 | 1.54E-08 | 22 |
| EFNB2 | Ephrin-B2 | NM_004093 | 2.16 | 1.32E-06 | 27 |
| EREG | Epiregulin | NM_001432 | 4.02 | <9.76E-05 | 20 |
| F3 | Coagulation factor III (thromboplastin, tissue factor) | NM_001993 | 3.81 | 1.61E-12 | 22 |
| HTRA3 | HtrA serine peptidase 3 | NM_053044 | 6.63 | 6.83E-16 | 22 |
| KRT80 | Keratin 80 | NM_182507 | 2.33 | 4.99E-04 | 21 |
| LAMA5 | Laminin, alpha 5 | NM_005560 | 5.19 | 5.73E-13 | 22 |
| NNMT | Nicotinamide N-methyltransferase | NM_006169 | 2.63 | 1.17E-08 | 19 20 23 24 |
| PIM1 | PIM-1 oncogene | NM_002648 | 2.46 | 6.5E-08 | 30 |
| PLAU | Plasminogen activator, urokinase | NM_002658 | 3.66 | <7.23E-12 | 19 20 22 25 30 |
| SPON2 | Spondin 2 | NM_012445 | 3.75 | 1.75E-12 | 22 |
| TGFB2 | Transforming growth factor beta 2 | NM_003238 | 3.83 | 4.12E-05 | 21 |
| TAGLN | Transgelin | NM_001001522 | 3.18 | 2.41E-08 | 30 |
| TGM2 | Transglutaminase 2 | NM_004613 | 2.87 | 2.18E-08 | 18 23 24 |
| TUBA1 | Tubulin, alpha 1 (testis specific) | NM_006000 | 2.63 | 7.05E-09 | 18 |
| WISP1 | WNT1 inducible signalling pathway protein 1 | NM_003882 | 2.34 | 1.72E-07 | 21 |