Fig. 1.
The development of hind paw reflex sensitivity to punctate mechanical stimuli in rats treated with ddC. Hind paw withdrawal thresholds to an electronic von Frey device measured following treatment with 50 mg/kg ddC (
n = 60) or saline sham control (■ n = 10). Data is shown at baseline and at time of peak hypersensitivity (days 19–21). Statistical significance of differences between groups (§p ≤ 0.05) was determined by a Kruskall–Wallis one-way analysis of variance (ANOVA) with Dunn's all pairwise multiple comparisons post hoc analysis where. Each value is the mean ± S.E.M.
