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. Author manuscript; available in PMC: 2009 Jun 23.
Published in final edited form as: J Invest Dermatol. 2008 Jul 17;129(1):79–88. doi: 10.1038/jid.2008.194

Figure 2. Most CD11c+ myeloid DCs are BDCA-1− in psoriasis lesional skin.

Figure 2

(a) The majority of CD11c+ cells in psoriatic dermis were BDCA-1−, while a small subset of CD11c+ cells co-expressed BDCA-1+. (b) BDCA-1 and BDCA-3 identified separate myeloid DC populations in the dermis. (c) Most BDCA-3+ cells co-expressed CD11c, and some BDCA-3 staining was observed on blood vessels. In all IF figures, single stained controls are above the merged image, white line denotes dermo-epidermal junction, dermal collagen fibers gave green autofluorescence, and antibodies conjugated with a fluorochrome often gave background epidermal fluorescence. Size bar = 100μm.