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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Muscle Nerve. 2009 Jul;40(1):19–31. doi: 10.1002/mus.21386

Figure 2. Relationship of sarcoplasmic TDP-43 immunoreactivity to other features.

Figure 2

(A1-A3) Adjacent sections from an IBM sample show sarcoplasmic areas of intense TDP-43 staining that are not immunoreactive for SMI31 and do not show fluorescence after Congo red staining. (B1-B3) Adjacent sections from an IBM sample show TDP-43 sarcoplasmic staining distinct from SMI31 and DAPI nuclear staining. (C,D) High magnification of TDP-43 immunoreactivity in a myofiber from IBM, with adjacent section showing H&E appearance of this myofiber.