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Role of S. aureus Stk1 during infection. Shown is the effect of stk1 deletion in strain SH1000 on S. aureus survival in mice. Bacterial counts of the parental SH1000 and ST1005 (Δstk1 mutant) strains were determined in the kidneys of CD1 mice (n = 6) 7 days after intravenous injection of 108 CFU. Each point is the result for one mouse. The bars represent mean CFU in two kidneys. *, P < 0.001 (Student's t test).
