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Physiological parameters under basal conditions
| Parameter | CD-KO | C | P Value |
|---|---|---|---|
| Urine ammonia, μmol/dl | 63±10 (6) | 86±5 (6) | <0.05 |
| Urine pH | 5.77±0.04 (6) | 5.74±0.05 (6) | NS |
| Urine volume, ml/day | 0.77±0.14 (6) | 0.81±0.11 (6) | NS |
| Serum HCO3−, mmol/l | 19.9±0.3 (5) | 19.4±1.1 (6) | NS |
| Body weight, g | 20.2±0.8 (12) | 19.9±0.3 (12) | NS |
Values are means ± SE. Numbers in parentheses are numbers of animals in each group. CD-KO, collecting duct-specific Rh glycoprotein (Rhcg) deletion; C, control; NS, not significant.
