Table 4.
Unadjusted and adjusted association between CRP and stroke severity (NIHSS, OCSP), stroke etiology (TOAST), outcomes (mRS, BI, mortality) and future vascular events in the 'Bergen stroke study' (n = 498)
| Subgroup | Unadjusted | Adjusted* | ||||||
| CRP categories: | 3–9.9 | 10+ | p | 3–9.9 | 10+ | p | ||
| NIHSS** | 7–13 | OR | 1.77 | 3.17 | 0.01 | 1.85 | 3.28 | 0.02 |
| 14+ | OR | 1.11 | 1.89 | 1.03 | 1.85 | |||
| OCSP (reference: LACI) | TACI | OR | 0.84 | 1.79 | 0.008 | 0.87 | 1.61 | 0.03 |
| PACI | OR | 1.15 | 0.63 | 1.23 | 0.63 | |||
| POCI | OR | 0.64 | 1.07 | 0.74 | 1.21 | |||
| TOAST (reference: Athero-thrombotic) | Cardioembolic | OR | 0.90 | 1.89 | 0.04 | 0.93 | 2.03 | 0.09 |
| Small vessel | OR | 0.67 | 0.81 | 0.67 | 1.06 | |||
| Other | OR | 0.38 | 1.65 | 0.49 | 3.86 | |||
| Unknown | OR | 0.53 | 0.73 | 0.53 | 0.90 | |||
| Poor outcome (mRS >2) |
OR | 1.2 | 2.2 | 0.01 | 1.04 | 1.07 | 0.98 | |
| Poor outcome (BI <95) |
OR | 1.26 | 2.08 | 0.03 | 1.02 | 1.18 | 0.88 | |
| Mortality | HR | 2.20 | 5.49 | 1.20E-06 | 2.31 | 3.47 | 0.002 | |
| Future Vascular Events | HR | 0.95 | 0.95 | 0.98 | 0.86 | 0.84 | 0.87 | |
NIHSS = National Institute of health Stroke Score
OCSP = Oxford Community Stroke Project Classification
TOAST = Trial of Org 10172 in Acute Stroke Treatment
mRS = Modified Rankin scale
BI = Barthel index
HR = Hazards ratio from Cox regression
OR = Hazards ratio from logistic regression
*Adjusted for age, sex, NIHSS, pre-existing diabetes and intravenous thrombolysis in categories
**Adjusted only for age and sex in categories