Table 1.
TH and GluR1 dual-labeled dendrites (significant changes from saline controls)
| VTA Region | Morphine paradigm | Cytoplasmic dendritic labeling | Plasmalemmal dendritic labeling | Synaptic labeling | MVB | Dendritic size | TH immunoreactivity |
|---|---|---|---|---|---|---|---|
| PB VTA | Acute | ↓ small, medium | ↑ small | ↑ # of labeled synapses | ↓ | ↑ | ↓ |
| Chronic | No change | No change | ↑ # of labeled synapses; ↑ # of gold particles | ↓ | ↑ | ↑ | |
| PN VTA | Acute | ↓ small, medium | No change | No change | No change | ↑ | No change |
| Chronic | No change | No change | ↑ # of labeled synapses | ↓ | ↓ | ↑ |
↑, Increase; ↓, decrease; #, number.