Figure 3.
Increased activity in the left DLPFC and the left VLPFC during the encoding of the second paired (2P) stimuli versus the second unpaired (2U) stimuli. Statistical activation maps illustrating greater activation (p < .01) during the encoding of 2P versus 2U stimuli are superimposed on sagittal (A) and coronal (B) slices of the mean anatomical scan images across all 13 subjects; arrows indicate left DLPFC (green) and left VLPFC (blue) clusters used for time-course analysis. (C) Time course of activity in the left DLPFC beginning with the onset of 2P stimuli (blue) and 2U stimuli (pink) demonstrating activity during item encoding, with increased activity during associative encoding. The time of stimulus presentation is represented by the light blue block. (D) Time course of activity in the left VLPFC for the same comparison demonstrates activity only during associative encoding, with no significant response during the encoding of individual items.