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. 2009 Apr 30;4(4):e5401. doi: 10.1371/journal.pone.0005401

Table 2. Top named genes differentially expressed (P<0.01) between primary tumors and metastasis.

Affymetrix probe set Gene Title Gene Symbol fold change, met vs primary (log2)
Higher in metastasis (ranked by fold change)
1426278_at interferon, alpha-inducible protein 27 Ifi27 2.034805214
1418588_at neurensin 1 Nrsn1 2.015696907
1423439_at phosphoenolpyruvate carboxykinase 1, cytosolic Pck1 2.008413051
1436504_x_at apolipoprotein A-IV Apoa4 1.899587267
1448226_at ribonucleotide reductase M2 Rrm2 1.856439628
1427465_at ATPase, Na+/K+ transporting, alpha 2 polypeptide Atp1a2 1.80166054
1419943_s_at cyclin B1 Ccnb1 1.718304491
1460347_at keratin 14 Krt14 1.650172294
1438009_at similar to histone 2a MGC73635 1.628484792
1455439_a_at lectin, galactose binding, soluble 1 Lgals1 1.619253423
1431164_at Ras-related GTP binding D Rragd 1.616979652
1451367_at COP9 (constitutive photomorphogenic) homolog, subunit 6 (Arabidopsis thaliana) Cops6 1.616770969
1426920_x_at integrin beta 1 (fibronectin receptor beta) Itgb1 1.607222931
1416301_a_at early B-cell factor 1 Ebf1 1.604511281
1422006_at eukaryotic translation initiation factor 2-alpha kinase 2 Eif2ak2 1.584624642
1448314_at cell division cycle 2 homolog A (S. pombe) Cdc2a 1.564221952
1420575_at metallothionein 3 Mt3 1.543842484
1419513_a_at ect2 oncogene Ect2 1.525512151
1456566_x_at RNA binding motif protein 14 Rbm14 1.496890793
1423607_at lumican Lum 1.4854932
Lower in metastasis (ranked by fold change)
1452543_a_at secretoglobin, family 1A, member 1 (uteroglobin) Scgb1a1 −5.605051087
1435386_at Von Willebrand factor homolog Vwf −4.501907686
1423436_at glutathione S-transferase, alpha 3 Gsta3 −3.815193669
1421802_at eosinophil-associated, ribonuclease A family, member 1 Ear1 −3.81250599
1454681_at RNA binding motif protein 35A Rbm35a −3.599463463
1416236_a_at epithelial V-like antigen 1 Eva1 −3.579430627
1422905_s_at flavin containing monooxygenase 2 Fmo2 −3.576820392
1419475_a_at ets homologous factor Ehf −3.487510424
1450494_x_at CEA-related cell adhesion molecule 1 Ceacam1 −3.394496
1423914_at RIKEN cDNA C630004H02 gene C630004H02Rik −3.049771708
1423323_at tumor-associated calcium signal transducer 2 Tacstd2 −3.037340132
1429626_at surfactant associated protein A1 Sftpa1 −2.893831126
1449081_at carboxylesterase 3 Ces3 −2.88430922
1426332_a_at claudin 3 Cldn3 −2.869993162
1422334_a_at surfactant associated protein A1 Sftpa1 −2.7988671
1417797_a_at RIKEN cDNA 1810019J16 gene 1810019J16Rik −2.785446923
1449184_at peptidoglycan recognition protein 1 Pglyrp1 −2.713447175
1418639_at surfactant associated protein C Sftpc −2.710279321
1417275_at myelin and lymphocyte protein, T-cell differentiation protein Mal −2.707840748
1421404_at chemokine (C-X-C motif) ligand 15 Cxcl15 −2.682133804