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The heme–FMN domain interface. Blue and yellow colors are assigned to the backbones for the heme and flavin domains, respectively. Some of the solvent molecules mediating domain–domain interaction are shown in red. The dotted lines represent hydrogen bonds and salt bridges. The Pro-382–Cys-400 part of the heme-binding peptide provides a direct through-bond electron transfer pathway from the FMN to the heme.
