Figure 7.
Interleukin-1β, -6 and -8, EGR1, CYR61 and CTGF mRNA levels in control fetuses and following VG5 and VG10 ventilation strategies. IL-1β, IL-6 and IL-8 (A) and EGR1, CYR61 and CTGF (B) mRNA levels in unventilated age-matched control fetuses and in preterm lambs mechanically ventilated from birth at 125 days of gestation with either 5 (VG5) or 10 (VG10) mL/kg. The values are mean ± SEM and expressed as a fold-change relative to the mean levels in unventilated control fetuses. The asterisks (*) represents values significantly greater (p < 0.001) than values before ventilation measured in age-matched control fetuses. The hash (#) represents values significantly greater than those in the VG5 lambs (p < 0.05).