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. 2009 Jan 9;58(4):803–812. doi: 10.2337/db08-1054

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© 2009 by the American Diabetes Association.

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.

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FIG. 4. — Castration reverses lipogenic rates in male and female adipocytes. Male and female mice were castrated or sham operated. Six weeks after surgery, adipocytes from PG (A and B) and SC (C and D) fat were isolated and stimulated with or without insulin in the presence of ¹⁴C-glucose for 90 min. Radioactivity was measured in the extracted lipids and normalized by total lipid content. n = 6 animals per group. **P < 0.05 by repeated-measures ANOVA. *P < 0.05 by Student's t test for point-to-point comparisons sham versus castrated.