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Interleukin-1beta (IL-1β) levels in the microglia culture medium after thrombin treatment. Cultured microglia were treated with either vehicle, thrombin (10 U/ml) or thrombin (10 U/ml) plus minocycline (Mino, 1 or 10 mM). Values are mean ±SD, # p<0.01 vs. the other groups.