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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: J Immunol. 2009 Mar 1;182(5):3039–3046. doi: 10.4049/jimmunol.0713598

Figure 4. IL-17-deficient mice exhibit decreased lesions volumes and lower parasite burdens after infection with L. major.

Figure 4

Infections were initiated in IL-17−/− and control BALB/c and C57BL/6 mice with 2 × 105 (A, C) or 1,000 (B, D) L. major metacyclic promastigotes and lesion volumes ere assessed weekly (A, B, mean ± SEM; n ≥ 10). At week 3 (high dose, C) and week 6 and 8 (low dose, D), mice were euthanized and lesional parasite loads were determined using limiting dilution assays. Dots represent numbers of parasites in single ears; bars show the arithmetic mean of all mice/group. Statistical differences between BALB/c strains are indicated by *, between IL-17−/− and C57BL/6 mice as # (*,#=p ≤ 0.05, **,##=p ≤ 0.005, ***,###=p ≤ 0.002).