Figure 1.

Bax-deficient mouse peritoneal macrophages display reduced apoptosis in vitro. A, Caspase-3 activity assay after 12-hour treatment with 7-KC. Relative fluorescent unit (RFU) was normalized to protein concentrations. Data represent 3 independent experiments. B, TUNEL staining after the treatment with 25-hydroxycholesterol (25-OHC) for 40 hours or staurosporine (STS) for 21 hours. *P<0.05 compared with the WT group.