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. 2009 Feb 9;184(3):399–408. doi: 10.1083/jcb.200810113

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© 2009 Rowe et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 3. — Snail1 is a master regulator of fibroblast gene expression programs. (A) Heat map of microarray data for three biological replicates of Snail1^fl/fl and Snail1^−/− fibroblasts. The 20 most highly up-regulated and down-regulated transcripts in Snail1^−/− fibroblasts are presented. The key on the bottom assigns heat map colors to the absolute gene expression value on a log2 scale. (B) GO terms identifying biological processes differentially expressed in Snai1^fl/fl and deficient fibroblasts. (C) List of motility- and invasion-associated genes regulated by Snail1 in fibroblasts.