Figure 2.
Elevated plus-maze behaviors of both adolescent and adult male and female rats from Exp. 1 following prior challenge with either ethanol (EtOH) or saline (SAL). For both (a) percent open arm time (%OAT) and (b) percent protected stretched attend postures (%PSAP), only a main effect of ethanol exposure emerged in these analyses, with elevated anxiety observed in ethanol-exposed compared to saline-exposed animals. A main effect of ethanol exposure was also observed for (c) number of closed arm entries (CAE), along with a main effect of sex. Inserts for each behavior are included to emphasize the overall withdrawal effect (collapsed across age and sex), with asterisks noting the increase in anxiety behaviors and decrease in activity following prior ethanol exposure.