Figure 1.
Bcl-2 and Bcl-xL prevent cell death in growth factor–deprived cells despite decreased glucose uptake. (A and B) Cells were cultured in IL3 or withdrawn from IL3 for (A) 6 or (B) 10 h and analyzed by immunoblot. (C) The expression of MyrAkt, Bcl-xL, and Bcl-2 was established by immunoblot. Cell survival (D) and glucose uptake (E) were determined at indicated times after IL3 withdrawal. Means of triplicate samples and SDs are shown for survival curves and SEs for glucose uptake. Data shown are representative of three or more experiments. *p < 0.05 by Student's t test of IL3 withdrawn samples compared with control (D) or + IL3 samples (E).