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Fractional synthesis rates (FSR) of skeletal muscle mitochondrial protein using plasma [13C]KIC (A) and tissue fluid [13C]leucine (B) as precursor pool enrichment, and as a percentage of mixed protein synthesis rates (C) in young, middle-aged, and old human subjects. Because no gender differences were observed, the male and female subjects are presented as one group. ∗, P < 0.05; ∗∗, P < 0.01 versus young.
