. 2008 Nov 14;21(1):29–42. doi: 10.1093/intimm/dxn120

Table 2.

Summary of statistically significant^a apoptosis-related features of CD8⁺CD127⁺ and CD8⁺CD127⁻ T cells^b

	CD8⁺CD127⁺			CD8⁺CD127⁻
	Annexin⁺	Caspase-8	Caspase-3	Annexin⁺	Caspase-8	Caspase-3
IL-2	↓	NC	↑	NC	↑	↑
IL-15	NC	↑	↑	NC	NC	↓
Anti-CD3	↑	↑	↑	↑	NC	↓
Anti-Fas	↑	NC	NC	NC	NC	↓
IL-2 + anti-CD3	↓	↓	↓	↓	NC	↑
IL-2 + anti-Fas	↓	↓	↑	NC	↑	↑
IL-15 + anti-CD3	NC	↓	↓	NC	↓	NC
IL-15 + anti-Fas	↑	↓	↑	↑	↓	NC

NC, no change;↑ = significantly increases apoptosis (P < 0.05); ↓ = significantly decreases apoptosis (P < 0.05).

Statistical significance was determined by the Student's t-test (P < 0.05).

Responses to cytokine, anti-CD3 or anti-Fas alone were compared with medium controls while responses involving cytokine pre-treatment followed by anti-Fas or anti-CD3 were compared with anti-Fas or anti-CD3 alone.