Table 2.
Univariate comparison of categorical ovarian cancer risk factors with p53 signature status among 75 BRCA+ women.
| Risk Factor | n | n (%), p53 negative | n (%), p53 positive | p-value, Chi-square |
|---|---|---|---|---|
| BRCA mutation: 1 | 39 | 24 (62) | 15 (38) | 0.35 |
| 2 | 33 | 23 (70) | 10 (30) | |
| History of chemotherapy: No | 47 | 30 (64) | 17 (36) | 0.93 |
| Yes | 28 | 17 (61) | 11 (39) | |
| Personal history of breast cancer: No | 42 | 27 (64) | 15 (36) | 0.40 |
| Yes | 33 | 20 (61) | 13 (39) | |
| Menopause Type: Surgery | 39 | 26 (67) | 13 (33) | 0.44 |
| Chemotherapy | 11 | 6 (55) | 5 (45) | |
| Smoking History: Never | 66 | 39 (59) | 27 (41) | 0.73 |
| Ever | 9 | 8 (89) | 1 (11) | |
| Tamoxifen Use: Never | 65 | 41 (63) | 24 (37) | 0.70 |
| Ever | 9 | 6 (67) | 3 (33) |