. Author manuscript; available in PMC: 2008 Dec 4.

Published in final edited form as: Biochemistry. 2007 Apr 19;46(19):5732–5740. doi: 10.1021/bi700300u

Table 3.

Relative shifts in active site residues of carbapenemases compared to non-carbapenemases

	Shifts (in Å) relative to SHV-1 (and TEM-1)
	OG:S130	OG1:T235	CA:S70	CA:N170	CA:E166	CA:N132	CA:T/V216
KPC-2	0.6(0.5)¹	1.7(1.0)	0.8(0.9)	0.6(0.5)	0.9(0.9)	0.5(0.5)	1.0(0.8)
NMC-A	0.7(0.4)	1.2(0.6)	0.5(0.5)	0.5(0.4)	0.4(0.3)	0.8(0.7)	1.5(1.3)
SME-1	0.8(0.6)	1.2(0.6)	0.7(0.7)	0.3(0.2)	0.6(0.6)	0.8(0.7)	1.5(1.3)

Carbapenemase shifts relative to the TEM-1 structure are all listed in parenthesis