Table 4.
Genotypic analysis of DRB1* associations
| Genotype | Analysis | Odds Ratio | 95% CI | P value |
|---|---|---|---|---|
| *08 |
1 vs 0a |
3.32 |
2.44 − 4.51 |
2.0*10−14 |
| *11 | 1 vs 0 | 0.32 | 0.26 − 0.39 | 2.1*10−26 |
| 2 vs 0 | 0.17 | 0.10 − 0.29 | 9.1*10−11 | |
| |
2 vs 1 |
0.54 |
0.31 − 0.93 |
0.025 |
| *13 |
1 vs 0 |
0.70 |
0.55 − 0.89 |
0.0031 |
| *11/*13 | vs 0 | 0.11 | 0.06 − 0.22 | 1.4*10−10 |
| vs *11 | 0.38 | 0.19 − 0.74 | 0.0043 | |
| vs *13 | 0.20 | 0.10 − 0.40 | 5.5*10−6 | |
| vs *11 or *13 | 0.30 | 0.16 − 0.59 | 0.00042 | |
| |
vs *11/*11 |
0.77 |
0.34 − 1.76 |
0.54 |
| *08/*11 | vs 0 | 0.94 | 0.50 − 1.76 | 0.85 |
| vs *08 | 0.34 | 0.17 − 0.69 | 0.0029 | |
| vs *11 | 2.81 | 1.48 − 5.34 | 0.0017 |
The effect of one or two copies of the genotype compared with 0 or 1 copy is shown for the different genotypes. Two copies of DRB1*08 and *13 are not included since the frequency of *08/*08 and *13/*13 homozygotes were <0.01.