Fig. 4.

Sensitivity of the automated method to mis-registration. The TRT (tract-specific ROI template) transferred to each subject is intentionally shifted along the X, Y, and Z axes and the matching (kappa value) between the automated and manual methods is measured. The results are for the CST (A), IFO (B), and FMa (C). The error bars represent standard deviations from 10[sm23] healthy volunteers. X[sm24], Y, and Z axes correspond to the right-left, anterior-posterior, and superior-inferior orientations, respectively.