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. Author manuscript; available in PMC: 2009 Feb 1.
Published in final edited form as: Hypertension. 2008 Jun 9;52(2):256–263. doi: 10.1161/HYPERTENSIONAHA.108.112706

Figure 5.

Figure 5

Renal tissue Western blot analysis of gp91phox proteins (Nox2) in mice treated with either vehicle or Ang II. The upper panel shows representative Western blot for gp91phox (58 kDa) and β-actin. The lower panel shows quantification of ratio of gp91phox to β-actin. gp91phox expression increased significantly in CCR2+/+ with Ang II-induced hypertension (p < 0.005, vehicle vs Ang II). gp91phox did not increase in CCR2−/− with Ang II-induced hypertension (p < 0.006, CCR2+/+ Ang II vs CCR2−/− Ang II). gp91phox expression in Ang II-induced hypertension was significantly higher in CCR2+/+ compared to CCR2−/− (p< 0.01; CCR2+/+ vs CCR2−/−). (n=6 per group).