Table 3.
Comparison of disease characteristics based on serogroup of Neisseria meningitidis
| N. meningitidisa | ||
| Serogroup B | Serogroup C | |
| Total number of children | 175 | 44 |
| Age in years | 2.8b | 6.0b |
| (0.1 to 17.9) | (0.1 to 16.5) | |
| PRISM score | 16 | 14 |
| (1 to 37) | (1 to 35) | |
| Predicted death rate (%)c | 8.9 | 4.9 |
| (0 to 100) | (0 to 100) | |
| Number of children with DIC (%) | 128 | 32 |
| (81) | (74) | |
| Number of PICU-free days | 24 | 25 |
| (0 to 28) | (0 to 27) | |
| Base excess (mmol/L) | -8 | -8.0 |
| (-21 to 4.4) | (-28 to 3) | |
| Lactate (mmol/L) | 4.2 | 3.5 |
| Geometric mean, 95% CI | 3.8 to 4.6 | 2.9 to 4.2 |
| C-reactive protein (mg/L) | 82d | 128d |
| (6 to 287) | (20 to 326) | |
| Fibrinogen (g/L) | 2.4 | 2.8 |
| (0.2 to 6.8) | (0.3 to 6.6) | |
| Platelet count (×103/μL) | 110 | 113 |
| (15 to 475) | (13 to 336) | |
| Leukocytes (×103/μL) | 8.8e | 12.2e |
| Geometric mean, 95% CI | 7.6 to 10.1 | 9.9 to 15.0 |
| Glucose (mmol/L) | 5.9 | 6.2 |
| Geometric mean, 95% CI | 5.4 to 6.5 | 5.5 to 6.9 |
aResults represent median (min-max) unless stated otherwise. bp < 0.001. cPredicted death rate was based on the Rotterdam score. dp < 0.01. ep < 0.05. CI, confidence interval; DIC, disseminated intravascular coagulation; PICU, paediatric intensive care unit; PRISM, Paediatric Risk of Mortality.