Fig. 1. Structures of the lipid A and Kdo regions of LPS in E. coli and F. tularensis.
Evidence for these structures has been presented elsewhere (3, 4, 36). A, the LPS molecules made by the heptose-deficient E. coli mutant WBB06; B, the Kdo-lipid A region of F. tularensis LPS; C, structure of the Kdo2-[4′-32P]lipid A substrate for the 1-phosphatase; D, structure of the Kdo2-[4′-32P]lipid IVA used to detect both the 4′-phosphatase and the 1-phosphatase.
