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Effects of resistin deficiency on body weight (A and B), fat (C), lipids (D–F), ketones (G), glucose (H), insulin (I), resistin (J), leptin (K), and adiponectin (L). Wild-type (WT) and resistin-knockout (RKO) mice were fed a high-fat diet for 10 wk, and ob/ob and ob/ob-RKO mice were fed normal chow. Data are means ± SE (n = 5/group). *P < 0.01 vs. WT; **P < 0.001 vs. WT; †P < 0.01 vs. ob/ob. Dotted line denotes level in WT mice on normal chow. NEFA, nonesterified fatty acids.
