TABLE 2.
Genetic factors studied in association with the development of GBS or Campylobacter-associated GBS
| Gene studied | Association with GBS | Association with Campylobacter-induced GBSa | Reference |
|---|---|---|---|
| MMP9 | Yes, severity | NS | 68 |
| TNFA | Yes, severity | NS | 68 |
| IL-10 | No | NS | 68 |
| IL-10 | No | NS | 68 |
| CD1 | Yes, incidence | NS | 37 |
| MBL2 | Yes, severity | NS | 70 |
| HLA class II | Yes, severity | NS | 71 |
| HLA-DRB1 | No | Nonsignificant association (trend) | 103 |
| HLA B54 | Yes, incidence | Yes, incidence | 95 |
| HLA-Cw1 | No | Yes, incidence | 95 |
| FCGR2A | Yes, incidence/severity | NS | 165 |
| FCGR3A | No | NS | 165 |
| FCGR3B | No | NS | 165 |
| FCGR3B | Yes, severity | NS | 170 |
| FCGR3B | Yes, severity | NS | 169 |
| IL-10 | Yes, incidence | NS | 115 |
| FAS/CD95 | Yes, GM1 antibodies | NS | 69 |
| CD14 | No | No | 56 |
| TLR4 | No | No | 56 |
| APOE | No | NS | 136 |
| TNFA | NS | Yes, incidence | 102 |
a
NS, not studied.