. Author manuscript; available in PMC: 2009 Apr 1.

Published in final edited form as: Magn Reson Imaging. 2008 Apr;26(3):379–392. doi: 10.1016/j.mri.2007.07.007

Table 3.

Statistical comparisons between maximum-shifted COSLOF Indices and PSI in five brain regions of three subject groups

A. Maximum-shifted COSLOF Indices CI^m (Mean±SD)
CI^m	AD		MCI		Control
Hippocampus ^nr	0.412 ± 0.075		0.390 ± 0.072		0.438 ± 0.054
Hippocampus ^rg	0.398 ± 0.061		0.362 ± 0.054		0.424 ± 0.037
White matter	0.304 ± 0.049		0.305 ± 0.056		0.280 ± 0.067
Gray matter	0.336 ± 0.063		0.331 ± 0.083		0.325 ± 0.055
CSF	0.307 ± 0.051		0.337 ± 0.069		0.282 ± 0.025
Pure noise region	0.233 ± 0.003		0.234 ± 0.006		0.232 ± 0.002
B. PSI θ_G (Mean±SD)
θ_G	AD		MCI		Control
Hippocampus ^nr	72.6 ± 11.3		58.6 ± 5.7		40.6 ± 8.4
Hippocampus ^rg	68.0 ± 14.1		58.9 ± 7.0		43.5 ± 10.1
White matter	74.1 ± 9.2		64.4 ± 14.7		77.9 ± 4.5
Gray Matter	60.5 ± 9.8		67.1 ± 11.5		70.7 ± 9.7
CSF	78.1 ± 7.9		73.8 ± 6.2		74.0 ± 12.3
Pure noise region	88.9 ± 1.6		88.2 ± 0.9		88.5 ± 1.5
C. One-way unbalanced ANOVA for CI^m and θ_G of three subject groups
Measurement	F_nr(2,23)	p-value_nr		F_rg(2,23)	p-value_rg
CI^m	0.941	0.4049		2.661	0.0913
θ_G	25.789	<0.0001		10.462	0.0006
D. Pairwise T-test between three subject groups
One-tail t-test for PSI ^nr			One-tail t-test for PSI^rg
AD vs. MCI ^**	p = 0.0047		AD vs. MCI		p = 0.1487
MCI vs. CONTROL ^**	p = 0.0001		MCI vs. CONTROL ^**		p = 0.0006
AD vs. CONTROL ^***	p < 0.0001		AD vs. CONTROL ^***		p = 0.0006
E. Kruskal-Wallis Nonparametric Tests for CI^m and θ_G of three subject groups
Measurement	H_nr	p-value_nr		H_rg	p-value_rg
CI^m	2.459	0.2924		4.073	0.1305
θ_G	17.939	0.0001		11.478	0.0032

nr – no CSF voxels regression, rg – with CSF voxels regression, COSLOF Indices presented in this article in all other regions have been calculated without CSF voxel regression.

indicates p < 0.05

^**

indicates p < 0.01

^***

indicates p < 0.001