Skip to main content
. 1998 Nov 24;95(24):14367–14372. doi: 10.1073/pnas.95.24.14367

Table 1.

Effect of chronic treatment with ETA receptor antagonist LU135252 on plasma levels of nitrate (NO3−), total cholesterol, VLDL, LDL, and HDL cholesterol and plasma triglycerides in apoE-deficient and C57BL/6 mice

Group ApoE deficient
C57BL/6
Control LU135252 Control LU135252
Plasma NO3−, μmol/liter 57.9  ± 4.0 80.0  ± 8.3* 93  ± 10.1† 92.2  ± 6.0
Total cholesterol, mmol/liter 16.5  ± 1.4 16.2  ± 0.6 3.8  ± 0.3† 6.0  ± 0.3*†
VLDL cholesterol, mmol/liter 1.0  ± 0.23 0.69  ± 0.06 0.24  ± 0.06† 0.27  ± 0.15†
LDL cholesterol, mmol/liter 15.1  ± 1.2 15.3  ± 0.6 0.52  ± 0.17† 1.0  ± 0.21†
HDL cholesterol, mmol/liter 0.4  ± 0.1 0.3  ± 0.03 2.9  ± 0.19† 4.77  ± 0.24*†
Triglycerides, mmol/liter 2.2  ± 0.54 1.5  ± 0.14 0.65  ± 0.07† 0.59  ± 0.03†

Data are means ± SEM. 

*P < 0.05 vs. control. 

†

P < 0.05 vs. apoE-deficient. 

VLDL, very low density lipoproteins; HDL, high density lipoprotein.