Table 1.
Changes in expression level (fold) of selected transcripts in 3T3/D3 cells (4 weeks after reprogramming)
| Name | Description | 3T3/D3 | Pattern |
|---|---|---|---|
| Somatic cell markers | |||
| LMNA | Nuclear lamin A | 0.045 | down |
| LMNB1 | Nuclear lamin B1 | 1.67 | NA |
| LMNB2 | Nuclear lamin B2 | 1.1 | NA |
| NPR3 | Atrionatriuretic peptide receptor | 0.009 | down |
| PRC1 | Protein regulator of cytokinesis | 0.004 | down |
| CKAP2 | Cytoskeleton assosciated protein2 | 0.001 | down |
| FIN15 | FGF inducible15 | 0.018 | down |
| Embryonic stem cell/pluripotency markers | |||
| Pou5f1 | POU domain class 5 (Oct4) | 14.3 | up |
| Nanog | Nanog | 43.4 | up |
| Sox2 | Sex determining region Y box2 | 3.4 | up |
| Dppa3 | Developmental pluripotency associated | 5.1 | up |
| Dppa5 | Developmental pluripotency associated | 3.8 | up |
| FOXD3 | Forkhead box D3 | 34.0 | up |
| Kit | kit oncogene | 9.6 | up |
| DAD1 | Defender against cell death | 54.0 | up |
| Gdf3 | Netrin G1 | 2.0 | up |
| S1c2a3 | Solute carrier family 2 | 3.2 | up |
| Chromatin structure/function | |||
| JARID1B | Jumonji interactive domain | 6.38 | up |
| Hist1H2bc | Histonel, H2bc | 32.3 | up |
| HBP1 | High mobility group box trans. Factor | 4.8 | up |
| HDAC11 | Histone deacetylase 11 | 4.2 | up |
| HDAC1 | Histone deacetylase 1 | 6.7 | down |
| SOAT1 | Sterol O acetyltransferase 1 | 3.2 | up |
| Atp6v0d1 | ATPase H+ transporting | 43.0 | up |
| CREB | cAMP response element binding protein | 3.8 | up |
| LSD1 | Lysine specific histone demethylase | 11.2 | down |
| Acaa1a | acetyl transferase | 3.8 | up |
| Dnmt1 | DNA methyltransferase | 5.6 | down |
| Suv39h2 | Histone demethylase | 6.9 | up |
| Smarcad1 | SWI/SNF-related regulator of chromatin | 17.6 | up |
| Smc2 | Structural maintenance of chromatin | 12.6 | down |
| Nusap1 | Nucleolar and spindle associated protein | 13.3 | down |