Table 2.
Results from SPM study: cross-sectional group differences at the time of decline.
| Cluster size | Coordinates* |
Z† | Functional area | Brodmann Area | ||
|---|---|---|---|---|---|---|
| x | y | z | ||||
| Reduced MRglc for NL-MCI relative to NL-NL | ||||||
| 124 | −47 | −34 | 6 | 2.78 | Superior temporal gyrus | 22 |
| Reduced MRglc for NL-AD relative to NL-NL | ||||||
| 1952 | 60 | −48 | 32 | 4.57 | Inferior parietal lobule | 40 |
| 58 | −54 | 35 | 4.32 | 40 | ||
| 614 | −48 | −55 | 38 | 3.68 | Inferior parietal lobule | 40 |
| −41 | −53 | 44 | 3.39 | 40 | ||
| 237 | −3 | −64 | 18 | 3.23 | Posterior cingulate gyrus | 31 |
| 177 | −63 | −36 | 1 | 3.42 | Middle temporal gyrus | 21 |
| Reduced MRglc for NL-AD relative to NL-MCI | ||||||
| 1043 | 53 | −52 | 32 | 4.12 | Inferior parietal lobule | 40 |
| 326 | −53 | −56 | 40 | 4.07 | Inferior parietal lobule | 40 |
| 323 | −4 | −67 | 20 | 3.25 | Posterior cingulate gyrus | 31 |
Coordinates from the atlas of Talairach and Tournoux [56]. x is the distance in mm to the right (+) or left (−) of midline; y is the distance anterior (+) or posterior (−) to the anterior commissure, and z is the distance superior (+) or inferior (−) to a horizontal plane through the anterior and posterior commissures.
Z values at p<.05, corrected for multiple comparisons.