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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Exp Hematol. 2008 Feb 4;36(4):513–521. doi: 10.1016/j.exphem.2007.12.002

Figure 2.

Figure 2

Transduced lin− marrow cells display significantly impaired competitive repopulating ability in 1100 cGy-conditioned hosts. Transduced lin− test cells from Bl/6 donors were mixed with freshly-isolated lin− competitor cells from Boy J donors, and the mixtures were transplanted into 1100 cGy-conditioned Boy J hosts. In the experiment shown in panel (A), 3 × 105 test cells were mixed with 3 × 105 competitor cells prior to transplantation; in the experiment shown in panel (B), 6 × 105 test cells were mixed with 2 × 105 competitor cells. Test cell chimerism is shown 4–5 months post-transplant from two independent experiments. N = 4 hosts for each parameter. *, P < 0.012 comparing fresh test cell chimerism to that of transduced test cells.